Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → 8-chloro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | Cyclopentadiene | HCID 7612 | — |
| 반응물 | 4-Chloroaniline | HCID 7812 | — |
| 반응물 | 2-Ketobutyrate | HCID 3593277 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 8-chloro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid ethyl ester | HCID 9965449 | 89% |
반응 단계
Compound 3 was prepared in a yield of 89% by the basic process from 5.0 mmol 4-chloroaniline, 5.5 mmol ethylglyoxalate solution (50% toluene), 15.0 mmol cyclopentadiene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06699877B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-0a43b64858bc4a909c3d85b6456cc7da |
| 출처 메모 | uspto-grants-2004_03 |