Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → 1,3-Dichloro-5,6,6a,7,8,12b-hexahydrobenzo[k]phenanthridine-6-carboxylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | 1,2-Dihydronaphthalene | HCID 9938 | — |
| 반응물 | 3,5-Dichloroaniline | HCID 12281 | — |
| 반응물 | 2-Ketobutyrate | HCID 3593277 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 1,3-Dichloro-5,6,6a,7,8,12b-hexahydrobenzo[k]phenanthridine-6-carboxylic acid ethyl ester | HCID 10199516 | 85% |
반응 단계
Compound 12 was prepared in a yield of 85% by the basic process from 5.0 mmol 3,5-dichloroaniline, 5.5 mmol ethylglyoxalate solution (50% toluene), 15.0 mmol 1,2-Dihydronaphthalene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06699877B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-3d54656f7e5948219183190a4e02e3bf |
| 출처 메모 | uspto-grants-2004_03 |