Trifluoroacetic acid → 5,7-Dichloro-4-o-tolyl-1,2,3,4-tetrahydroquinoline-2-carboxylic acid ethyl ester
반응식
[Cl:1][C:2]1[CH:3]=[C:4]([CH:6]=[C:7]([Cl:9])[CH:8]=1)[NH2:5].[CH2:10]([C:12](=O)[C:13]([O-:15])=[O:14])[CH3:11].[CH3:17][C:18]1[CH:25]=[CH:24][CH:23]=[CH:22][C:19]=1C=C.F[C:27](F)(F)[C:28](O)=O>C(#N)C>[CH2:27]([O:15][C:13]([CH:12]1[CH2:10][CH:11]([C:19]2[CH:22]=[CH:23][CH:24]=[CH:25][C:18]=2[CH3:17])[C:3]2[C:4](=[CH:6][C:7]([Cl:9])=[CH:8][C:2]=2[Cl:1])[NH:5]1)=[O:14])[CH3:28]참가 물질
6
실험 절차
Compound 16 was prepared by the basic process from 5.0 mmol 3,5-dichloroaniline, 5.5 mmol ethylglyoxalate solution (50% toluene), 15.0 mmol 2-methylstyrene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile.
출처 및 근거
- ORD 기록
- ord-789bdd48cb9d4fae8eea910eb6e08d9b
- 출처 데이터셋
- uspto-grants-2004_03
- 특허 번호
- US06699877B2
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