Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → 6-Chloro-4-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline-2-carboxylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | 4-Chloroaniline | HCID 7812 | — |
| 반응물 | 4-Fluorostyrene | HCID 67883 | — |
| 반응물 | 2-Ketobutyrate | HCID 3593277 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 6-Chloro-4-(4-fluorophenyl)-1,2,3,4-tetrahydroquinoline-2-carboxylic acid ethyl ester | HCID 10131727 | — |
반응 단계
Compound 51 was prepared by the basic process from 5.0 mmol 4-chloroaniline, 5.5 mmol ethylglyoxalate solution (50% toluene), 15.0 mmol 4-fluorostyrene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06699877B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-a0357a15aef04c8a907f21ba74c90826 |
| 출처 메모 | uspto-grants-2004_03 |