Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
9-Fluorenylmethyl chloroformate → 9H-9-fluorenylmethyl N-[4-(4-amino-2-butyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)butyl]carbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 9-Fluorenylmethyl chloroformate | HCID 34367 | — |
| 반응물 | 4-(4-amino-2-butyl 1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)butaneamine | HCID 12992616 | — |
| 생성물 | 9H-9-fluorenylmethyl N-[4-(4-amino-2-butyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)butyl]carbamate | HCID 12018531 | 70.8% |
반응 단계
Using the general method of Example 55, 9-fluorenylmethyl chloroformate (0.085 g, 0.33 mmol) was reacted with 4-(4-amino-2-butyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)butaneamine (0.105 g, 0.33 mmol) to provide 0.125 g of 9H-9-fluorenylmethyl N-[4-(4-amino-2-butyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)butyl]carbamate as a white powder. Analysis: Calculated for C32H34N6O2+¼H2O: %C, 71.29; %H, 6.45; %N, 15.59. Found: %C, 70.99; %H, 6.35; %N, 15.55.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06699878B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-59a44c3dbf5342a19ced7717234b0211 |
| 출처 메모 | uspto-grants-2004_03 |