Methylamine → 1-(2-Methylamino-3,5-dinitrophenyl)-2-propanol

HRID 4759

반응식

HRID 4759 반응식
[N+:1]([C:4]1[CH:5]=[C:6]([N+:14]([O-:16])=[O:15])[C:7]2[O:11][CH:10]([CH3:12])[CH2:9][C:8]=2[CH:13]=1)([O-:3])=[O:2].[CH3:17][NH2:18]>C(O)C>[CH3:17][NH:18][C:7]1[C:6]([N+:14]([O-:16])=[O:15])=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:13][C:8]=1[CH2:9][CH:10]([OH:11])[CH3:12]

참가 물질

4

반응물 2

HCID 6329MethylamineHCID 198363332-Methyl-5,7-dinitro-2,3-dihydro-1-benzofuran

생성물 1

HCID 198363251-(2-Methylamino-3,5-dinitrophenyl)-2-propanol

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

0.056 Mole (12.5 g) of 2,3-dihydro-5,7-dinitro-2-methyl-benzofuran is suspended in 100 ml of a 33% strength solution of methylamine in ethanol. After 10 hours' stirring at room temperature in a sealed Erlenmeyer, the reaction mixture is brought for 30 minutes to the refluxing temperature of the alcohol. After the mixture is cooled, the expected product precipitates. It is drained, washed with alcohol and then recrystallized from 50 ml of 96° strength ethanol. After being dried, 0.047 mole (12 g) is obtained of a product which melts at 132° C.

후처리

  1. temperatureAfter the mixture is cooled
  2. customthe expected product precipitates
  3. washwashed with alcohol
  4. customrecrystallized from 50 ml of 96° strength ethanol
  5. customAfter being dried
  6. custom0.047 mole (12 g) is obtained of a product which melts at 132° C.

출처 및 근거

ORD 기록
ord-52be2b750bf64c28aee0f8bfed4840c7
출처 데이터셋
uspto-grants-1988_02
특허 번호
US04727192

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