참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Pivalaldehyde | HCID 12417 | — |
| 반응물 | Sulfuric acid magnesium salt (1:1) | HCID 24083 | — |
| 반응물 | L-Alanine ethyl ester | HCID 76507 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N-neopentylidene-L-alanine ethyl ester | HCID 11412788 | — |
반응 단계
Step-2. L-Alanine ethyl ester from step-1 (9 g) was dissolved in 150 ml anhydrous CH2Cl2. The solution was cooled to 0° C. MgSO4 (10.17 g) was added to the solution followed by addition of pivalaldehyde (6.95 g). The reaction mixture was allowed to warm to room temperature and stirred overnight. The reaction mixture was filtered and the filtrate was evaporated to give 11.2 g of N-neopentylidene-L-alanine ethyl ester. The product was used for next step without further purification. MS: 186 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06699888B2 |
|---|
| 출처 데이터셋 | uspto-grants-2004_03 |
|---|
| ORD ID | ord-ab9b76fdbc7743159f62fc351f2ad4f3 |
|---|
| 출처 메모 | uspto-grants-2004_03 |
|---|
