Sodium Sulfite → Sodium 3-trifluoromethylbenzylsulfonate

HRID 476517노트

반응식

HRID 476517 반응식
[F:1][C:2]([F:12])([F:11])[C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH2:6]Cl.[S:13]([O-:16])([O-:15])=[O:14].[Na+:17].[Na+]>O>[F:1][C:2]([F:12])([F:11])[C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH2:6][S:13]([O-:16])(=[O:15])=[O:14].[Na+:17]

참가 물질

4

반응물 2

HCID 24437Sodium SulfiteHCID 697163-(Trifluoromethyl)benzyl chloride

생성물 1

HCID 23700704Sodium 3-trifluoromethylbenzylsulfonate수율 90.5%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A mixture containing 50 g of 3-trifluoromethylbenzyl chloride and 32.4 g of sodium sulfite in 200 ml of water was refluxed for five hours and then concentrated by evaporation. The concentrate was then filtered to collect the precipitate (product). The precipitate was then washed with ethyl ether and then dried in a vacuum oven affording 61 g of sodium 3-trifluoromethylbenzylsulfonate.

후처리

  1. temperaturewas refluxed for five hours
  2. concentrationconcentrated by evaporation
  3. filtrationThe concentrate was then filtered
  4. customto collect the precipitate (product)
  5. washThe precipitate was then washed with ethyl ether
  6. customdried in a vacuum oven

출처 및 근거

ORD 기록
ord-3035ba2ef0a1410d9769ed450dd25250
출처 데이터셋
uspto-grants-1989_12
특허 번호
US04885027

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