Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosphorus oxychloride → 3-(Trifluoromethyl)phenylmethanesulfonyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosphorus oxychloride | HCID 24813 | — |
| 반응물 | Sodium 3-trifluoromethylbenzylsulfonate | HCID 23700704 | — |
| 생성물 | 3-(Trifluoromethyl)phenylmethanesulfonyl chloride | HCID 2794646 | 90.2% |
반응 단계
10 g of sodium 3-trifluoromethylbenzylsulfonate was slowly added to 17.7 ml (29.1 g) of phosphorous oxychloride. The resulting slurry was stirred at 100° to 105° C. for five hours. The reaction mixture was then cooled and filtered. The filter cake was washed with methylene chloride, the washings were combined with the filtrate and then evaporated to dryness affording 8.9 g of 3-trifluoromethylbenzylsulfonyl chloride.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04885027 |
| 출처 데이터셋 | uspto-grants-1989_12 |
| ORD ID | ord-51a77baf777e493a98ac7c412476fd90 |
| 출처 메모 | uspto-grants-1989_12 |