HCID 14405656, 화합물 → HCID 14405658, 화합물

HRID 476629노트

반응식

HRID 476629 반응식
[I-].[CH3:2][N+:3]1[CH:8]=[CH:7][C:6]([C:9]([N:11]2[CH2:20][CH2:19][C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[CH2:12]2)=[O:10])=[CH:5][CH:4]=1>[Pt]=O.CO>[CH3:2][N:3]1[CH2:4][CH2:5][CH:6]([C:9]([N:11]2[CH2:20][CH2:19][C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[CH2:12]2)=[O:10])[CH2:7][CH2:8]1

참가 물질

4

반응물 1

HCID 14405656HCID 14405656, 화합물

생성물 1

HCID 14405658HCID 14405658, 화합물

시약·촉매·용매 2

HCID 82844Platinum oxide (PtO)촉매HCID 887Methanol용매

실험 절차

4 g (10.5 mmol) of 1-methyl-4-[(1,2,3,4-tetrahydro-2-isoquinolyl)carbonyl]pyridinium iodide and 0.4 g of platinum oxide are introduced into 250 ml of methanol, and the mixture is subjected to hydrogenation for 12 h under a pressure of approximately 0.41 MPa. The catalyst is filtered off, the solvent evaporated off and the residue neutralized, and an oil is obtained which crystallizes and which is used without further treatment in the following stage.

후처리

  1. filtrationThe catalyst is filtered off
  2. customthe solvent evaporated off
  3. customthe residue neutralized, and an oil is obtained which
  4. customcrystallizes

출처 및 근거

ORD 기록
ord-593e8fa1276945d694536e39166aafb6
출처 데이터셋
uspto-grants-1989_12
특허 번호
US04885302

반응 노트

불러오는 중…