참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Potassium Dichromate | HCID 24502 | — |
| 반응물 | 4-(4-Chloro-benzylamino)-cyclohexanol | HCID 13670658 | — |
| 생성물 | 4-[N-(4-Chloro-benzyl)-amino]-cyclohexanone | HCID 13670664 | — |
반응 단계
23.9 g (0.1 Mol) of 4-[N-(4-chlorobenzyl)-amino]-cyclohexanol are suspended in 125 ml of ice water and 32 ml of concentrated sulphuric acid are added. Then 29.4 g (0.1 Mol) of potassium dichromate are added in 2 batches and the mixture is heated for 5 hours at 50° C. It is then cooled, made alkaline with sodium hydroxide solution and extracted with chloroform. After concentration, a yellowish oily liquid is obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04886812 |
|---|
| 출처 데이터셋 | uspto-grants-1989_12 |
|---|
| ORD ID | ord-874c5a08b0844fab87f211f243ad1ec2 |
|---|
| 출처 메모 | uspto-grants-1989_12 |
|---|
