참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrogen Bromide | HCID 260 | — |
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | 1-(2,5-Dimethyl-1,3-oxazol-4-yl)ethan-1-one | HCID 14738583 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 2-Bromo-1-(2,5-dimethyloxazol-4-yl)ethanone | HCID 14076232 | — |
반응 단계
2.8 g (0.02 mol) of 2,5-Dimethyl-4-acetyl-oxazole are dissolved in 30 ml of glacial acetic acid, and 3 ml of a 35% strength solution of hydrogen bromide in glacial acetic acid are added. The mixture is heated to 100° C. and, over the course of 1 hour, a solution of 3.2 g (0.02 mol) of bromine in 10 ml of glacial acetic acid is added. After a further 2 hours the solvent is removed, and the residue is triturated with 50 ml of ether and filtered off with suction.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04886814 |
|---|
| 출처 데이터셋 | uspto-grants-1989_12 |
|---|
| ORD ID | ord-68dedfacc2014f55aebfa61493da6dbe |
|---|
| 출처 메모 | uspto-grants-1989_12 |
|---|
