Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Hydroxyphenylacetone → N-[2-(4-Hydroxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-trifluoromethylthiazol-4-yl)ethanamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Hydroxyphenylacetone | HCID 7019274 | — |
| 반응물 | 4-Thiazolemethanol, alpha-(aminomethyl)-2-(trifluoromethyl)- | HCID 14076239 | — |
| 생성물 | N-[2-(4-Hydroxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-trifluoromethylthiazol-4-yl)ethanamine | HCID 19974300 | — |
반응 단계
Prepared by analogy to Example 13 by reaction of 2-hydroxy-2-(2-trifluoromethyl-thiazol-4-yl)ethanamine with 4-hydroxyphenyl-propan-2-one followed by purification of the base on a silica gel column using chloroform/methanol=9:1 as eluant.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04886814 |
| 출처 데이터셋 | uspto-grants-1989_12 |
| ORD ID | ord-f26fb1f213af4f42a767a3477cc60d56 |
| 출처 메모 | uspto-grants-1989_12 |