Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl [(4-Chlorophenyl)thio]acetate → Diethyl 5-(4-chlorophenylthio)-2-dimethylamino-2,4-hexadienedioate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl [(4-Chlorophenyl)thio]acetate | HCID 257604 | — |
| 반응물 | Sodium ethoxide | HCID 2723922 | — |
| 반응물 | N-(dimethylamino-3-ethoxycarbonylpropenylidene)-N-methylmethanaminium tetrafluoroborate | HCID 86743575 | — |
| 반응물 | Diethyl 2-dimethylamino-5-phenylthio-2,4-hexadienedioate | HCID 86743580 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Diethyl 5-(4-chlorophenylthio)-2-dimethylamino-2,4-hexadienedioate | HCID 53649134 | 99.3% |
반응 단계
The procedure is as in Example 2 for the preparation of diethyl 2-dimethylamino-5-phenylthio-2,4-hexadienedioate, starting with N-(3-dimethylamino-3-ethoxycarbonylpropenylidene)-N-methylmethanaminium tetrafluoroborate (14.3 g), a 2M ethanolic solution of sodium ethylate (25 cc) and ethyl (4-chlorophenylthio)acetate (11.5 g) in ethanol (100 cc). Diethyl 5-(4-chlorophenylthio)-2-dimethylamino-2,4-hexadienedioate (19 g) is thereby obtained, and is used in the crude state in the subsequent phases.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04886835 |
| 출처 데이터셋 | uspto-grants-1989_12 |
| ORD ID | ord-1c3675ddc668401cbdb83c0864a75dbe |
| 출처 메모 | uspto-grants-1989_12 |