Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl (phenethylthio)acetate → Ethyl 5-dimethylamino-5-phenyl-2-phenethylthio-2,4-pentadienoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl (phenethylthio)acetate | HCID 304016 | — |
| 반응물 | Sodium ethoxide | HCID 2723922 | — |
| 반응물 | N-(3-dimethylamino-3-phenylpropenylidene)-N-methylmethanaminium tetrafluoroborate | HCID 75556698 | — |
| 반응물 | Ethyl 5-dimethylamino-5-phenyl-2-phenylthio-2,4-pentadienoate | HCID 86743587 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Ethyl 5-dimethylamino-5-phenyl-2-phenethylthio-2,4-pentadienoate | HCID 86743602 | — |
반응 단계
The procedure is as in Example 24 for the preparation of ethyl 5-dimethylamino-5-phenyl-2-phenylthio-2,4-pentadienoate, starting with N-(3-dimethylamino-3-phenylpropenylidene)-N-methylmethanaminium tetrafluoroborate (5.8 g), a 2M ethanolic solution of sodium ethylate (10 cc) and ethyl (phenethylthio)acetate (4.5 g) in ethanol (50 cc). After purification by chromatography on a silica column with dichloromethane as eluent, ethyl 5-dimethylamino-5-phenyl-2-phenethylthio-2,4-pentadienoate (4.5 g) is obtained in the form of a yellow oil, and is used in the crude state in the subsequent syntheses.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04886835 |
| 출처 데이터셋 | uspto-grants-1989_12 |
| ORD ID | ord-2ff60aa7020648b68f550d40016ce591 |
| 출처 메모 | uspto-grants-1989_12 |