Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl Chloride → 5-(benzylsulfanyl)-4H-1,2,4-triazol-3-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl Chloride | HCID 7503 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 5-amino-1H-1,2,4-triazole-3-thiol | HCID 178509296 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 5-(benzylsulfanyl)-4H-1,2,4-triazol-3-amine | HCID 737272 | 90.6% |
반응 단계
3-Amino-5-mercapto-1,2,4-triazole (40.36 g) was treated at room temperature with sodium hydroxide (13.9 g) in ethanol (450 ml), and benzyl chloride (44.3 g) was added. The mixture was stirred overnight, and was then filtered. The ethanol was evaporated off, and the residue was recrystallised from ethyl acetate to give 64.97 g of the desired product, mp 104° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04889553 |
| 출처 데이터셋 | uspto-grants-1989_12 |
| ORD ID | ord-b82cfc36a6374223bdd0d890c06b2c86 |
| 출처 메모 | uspto-grants-1989_12 |