2-Chloropyrimidine → HCID 19872288, 화합물

반응식

[CH2:1]([S:8][C:9]1[N:13]=[C:12]([S:14][CH3:15])[NH:11][N:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[C:17]1[N:22]=[CH:21][CH:20]=[CH:19][N:18]=1>>[CH2:1]([S:8][C:9]1[N:13]=[C:12]([S:14][CH3:15])[N:11]([C:17]2[N:22]=[CH:21][CH:20]=[CH:19][N:18]=2)[N:10]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 744042-Chloropyrimidine

HCID 178503580HCID 178503580, 화합물

생성물 1

HCID 19872288HCID 19872288, 화합물

실험 절차

The product of stage (a) (50 g) was treated with 2-chloropyrimidine (24.4 g) in a method analogous to that of Example F, to give, after chromatographic separation of two products, 23.6 g of the desired product.

후처리

customto give
customafter chromatographic separation of two products, 23.6 g of the desired product

출처 및 근거

ORD 기록: ord-46190c8f1da14c1a8cb9abdc2e881651
출처 데이터셋: uspto-grants-1989_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04889553

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