2-methoxydibenzo[b,e]oxepin-11(6H)-one → HCID 677495, 화합물

HRID 477782노트

반응식

HRID 477782 반응식
C[O:2][C:3]1[CH:18]=[CH:17][C:6]2[O:7][CH2:8][C:9]3[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=3[C:11](=[O:12])[C:5]=2[CH:4]=1.Cl.N1C=CC=CC=1>O>[OH:2][C:3]1[CH:18]=[CH:17][C:6]2[O:7][CH2:8][C:9]3[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=3[C:11](=[O:12])[C:5]=2[CH:4]=1

참가 물질

4

반응물 2

HCID 6779422-methoxydibenzo[b,e]oxepin-11(6H)-oneHCID 10176127Pyridinium chloride

생성물 1

HCID 677495HCID 677495, 화합물수율 79.7%

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
180 °C

실험 절차

A mixture of 20 g of 2-methoxy-6,11-dihydrodibenz[b,e]oxepin-11-one and 150 g of pyridine hydrochloride is stirred with heating at 180° C for 2 hours. The solution is poured into 2 liter of water with stirring to give 15 g of 2-hydroxy-6,11-dihydrodibenz[b,e]oxepin-11-one. Mass spectrum m/z: 226(M+), melting point: 165°-166° C. (recrystallized from ethanol).

후처리

  1. stirringwith stirring

출처 및 근거

ORD 기록
ord-2b2c9985ff50414d9021007233e6ec85
출처 데이터셋
uspto-grants-1989_12
특허 번호
US04889858

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