Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Lawesson's reagent → 7-nitro-1(2H)-phthalazinethione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Lawesson's reagent | HCID 87949 | — |
| 반응물 | 7-Nitrophthalazin-1(2h)-one | HCID 277729 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 7-nitro-1(2H)-phthalazinethione | HCID 19913710 | — |
반응 단계
13.9 g of 7-nitro-1(2H)-phthalazinone and 16.3 g of Lawesson reagent in 170 ml of acetonitrile are heated under reflux for 45 minutes. The reaction mixture is filtered while hot. The filtrate is cooled in an ice-bath and the crystals obtained are removed by filtration under suction. After drying in vacuo and recrystallization there is obtained 7-nitro-1(2H)-phthalazinethione as yellow crystals of m.p. 233+-234° (methanol/acetonitrile).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04889854 |
| 출처 데이터셋 | uspto-grants-1989_12 |
| ORD ID | ord-50d8a50fdbe1468396f82690e98f86ca |
| 출처 메모 | uspto-grants-1989_12 |