Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-(4-(Trifluoromethyl)phenyl)thiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Acetaldehyde, bromo- | HCID 105131 | — |
| 반응물 | 4-(Trifluoromethyl)thiobenzamide | HCID 2734823 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-(4-(Trifluoromethyl)phenyl)thiazole | HCID 14601969 | 49.3% |
반응 단계
In a manner similar to Step B of Example 1, the reaction of 10.0 grams (0.0487 mole) of (4-trifluoromethylphenyl)thiocarboxamide, 125 ml of ethanol, 8.35 grams (0.0490 mole) of bromoacetaldehyde, and 2 ml of concentrated hydrochloric acid produced 5.5 grams of 2-(4-trifluoromethylphenyl)thiazole as a solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04889867 |
| 출처 데이터셋 | uspto-grants-1989_12 |
| ORD ID | ord-b34f6ddb17ac42a98ce05c0042e80386 |
| 출처 메모 | uspto-grants-1989_12 |