HCID 178419031, 화합물 → HCID 178418735, 화합물

HRID 478185

반응식

HRID 478185 반응식
C([O:8][C:9]1[CH:10]=[C:11]([NH:15][C:16]([NH2:18])=[NH:17])[CH:12]=[CH:13][CH:14]=1)C1C=CC=CC=1>CCO.[Pd]>[OH:8][C:9]1[CH:10]=[C:11]([NH:15][C:16]([NH2:18])=[NH:17])[CH:12]=[CH:13][CH:14]=1

참가 물질

4

반응물 1

HCID 178419031HCID 178419031, 화합물

생성물 1

HCID 178418735HCID 178418735, 화합물

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

To a solution of N-(3-benzyloxy-phenyl)guanidine (5.0 g, 20.6 mmol) in EtOH (150 mL) was added palladium on carbon (10%, wet, 50% water, 0.5 g)). The mixture was stirred under hydrogen atmosphere overnight. The reaction was filtered through a plug of celite and the filtrate concentrated in vacuo. with toluene azeotroping to affored the desired material (2.83 g, 91%). 1H NMR (MeOH-d4) δ6.4-7 (m, 4H)

후처리

  1. filtrationThe reaction was filtered through a plug of celite
  2. concentrationthe filtrate concentrated in vacuo

출처 및 근거

ORD 기록
ord-d6c02952b6ab4954bab6ec20e5471e3f
출처 데이터셋
uspto-grants-2003_11
특허 번호
US06642227B2

연결된 노트

불러오는 중…