Sodium Nitrate → 4-Bromo-3-nitrobenzaldehyde

HRID 478288

반응식

HRID 478288 반응식
[N+:1]([O-:4])([O-])=[O:2].[Na+].[Br:6][C:7]1[CH:14]=[CH:13][C:10]([CH:11]=[O:12])=[CH:9][CH:8]=1>S(=O)(=O)(O)O>[Br:6][C:7]1[CH:14]=[CH:13][C:10]([CH:11]=[O:12])=[CH:9][C:8]=1[N+:1]([O-:4])=[O:2]

참가 물질

4

반응물 2

HCID 24268Sodium NitrateHCID 707414-Bromobenzaldehyde

생성물 1

HCID 8087924-Bromo-3-nitrobenzaldehyde수율 95%

시약·촉매·용매 1

HCID 1118Sulfuric Acid용매

반응 조건

온도
10 °C

실험 절차

A suspension of sodium nitrate (1.37 g, 16.2 mmol) in concentrated sulfuric acid (15 mL) was stirred at 10° C. until a homogeneous solution was obtained. The solution was treated with 4-bromobenzaldehyde (2.50 g, 13.5 mmol) in portionwise fashion over a 20 minute period. The solution was poured onto ice (50 g) and the resulting pale yellow precipitate was collected by filteration. The precipitate was washed with copious amounts of water then dried at 30° C. under reduced pressure to provide the title compound as a pale yellow solid (2.95 g, 12.8 mmol, 95%).

후처리

  1. customwas obtained
  2. additionThe solution was poured onto ice (50 g)
  3. customthe resulting pale yellow precipitate was collected by filteration
  4. washThe precipitate was washed with copious amounts of water
  5. customthen dried at 30° C. under reduced pressure

출처 및 근거

ORD 기록
ord-795925d01a8d41a0be58dadcd0128125
출처 데이터셋
uspto-grants-2003_11
특허 번호
US06642222B2

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