Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Methylpiperazine → Rac-cis-(3-fluoro-5-trifluoromethyl-phenyl)-[4-(4-methyl-piperazin-1-yl)-3-phenyl-piperidin-1-yl]-methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Methylpiperazine | HCID 53167 | — |
| 반응물 | 3-Fluoro-5-(trifluoromethyl)benzoyl chloride | HCID 519364 | — |
| 반응물 | 1-Benzyl-3-phenylpiperidin-4-one | HCID 11817956 | — |
| 생성물 | Rac-cis-(3-fluoro-5-trifluoromethyl-phenyl)-[4-(4-methyl-piperazin-1-yl)-3-phenyl-piperidin-1-yl]-methanone | HCID 131724196 | — |
반응 단계
The title compound, MS: m/e=450.5 (M+H+), was prepared in accordance with the general method of example 26 from 1-benzyl-3-phenyl-piperidin-4-one, N-methyl-piperazine and 3-fluoro-5-trifluoromethyl-benzoyl chloride.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06642226B2 |
| 출처 데이터셋 | uspto-grants-2003_11 |
| ORD ID | ord-dbc47a6288dd4a21a98a2f2659bd951e |
| 출처 메모 | uspto-grants-2003_11 |