Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HCID 53406803, 화합물 → Methyl 4-(piperazin-1-yl)benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | HCID 53406803 | HCID 53406803 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladiumcarbon | HCID 14818447 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Methyl 4-(piperazin-1-yl)benzoate | HCID 15429161 | — |
반응 단계
4-(4-Benzyl-piperazin-1-yl)-benzoic acid methyl ester (19.4 mmol) is dissolved in methanol (150 ml) and Pd/charcoal is added (0.6 g). The mixture is stirred in a hydrogen atmosphere until consumption has ceased. The catalyst is filtered off and the filtrate evaporated. The residue is suspended in diethylether/pentane and the solid filtered of and dried (vacuum). A powder with mp. 95-97° C. is obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06642239B2 |
| 출처 데이터셋 | uspto-grants-2003_11 |
| ORD ID | ord-305fc93190cc47c78bc1b9788ef9a944 |
| 출처 메모 | uspto-grants-2003_11 |