Sodium bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylate → bicyclo2.2.1heptane-2,3-dicarboxylic acid, disodium salt

HRID 478879

반응식

HRID 478879 반응식
[CH:1]12[CH2:7][CH:4]([CH:5]=[CH:6]1)[CH:3]([C:8]([O-:10])=[O:9])[CH:2]2[C:11]([O-:13])=[O:12].[Na+:14].[Na+]>O.[Pd]>[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[CH:3]([C:8]([O-:10])=[O:9])[CH:2]2[C:11]([O-:13])=[O:12].[Na+:14].[Na+:14]

참가 물질

4

반응물 1

HCID 21908873Sodium bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylate

생성물 1

HCID 21981355bicyclo2.2.1heptane-2,3-dicarboxylic acid, disodium salt

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 962Water용매

실험 절차

To a solution of disodium bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylate (10.0 g) in water (100 g) was added 0.5 g palladium on activated carbon (5 wt%). The mixture was transferred into a Parr reactor and was subjected to hydrogenation (50 psi, room temperature) for 8 hours. The activated carbon was filtered out, and the water was removed in vacuo at 75° C. The resulting product (m.p >300° C.) was dried and milled. NMR and IR analyses were consistent with that of the expected structure.

후처리

  1. filtrationThe activated carbon was filtered out
  2. customthe water was removed in vacuo at 75° C
  3. customThe resulting product (m.p >300° C.) was dried
  4. custommilled

출처 및 근거

ORD 기록
ord-8d7469250ebd4d85a80499fcf856614c
출처 데이터셋
uspto-grants-2003_11
특허 번호
US06642290B1

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