(4-Benzyl-piperidin-1-yl)-acetic acid → HCID 18002785, 화합물

HRID 478908노트

반응식

HRID 478908 반응식
Cl.NCC([C:6]1[CH:14]=[C:13]2[C:9]([CH2:10][C:11](=[O:15])[NH:12]2)=[CH:8][CH:7]=1)=O.[CH2:16]([CH:23]1[CH2:28][CH2:27][N:26]([CH2:29][C:30]([OH:32])=O)[CH2:25][CH2:24]1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH2:16]([CH:23]1[CH2:24][CH2:25][N:26]([CH2:29][C:30]([NH:26][CH2:29][C:30](=[O:32])[C:7]2[CH:8]=[C:9]3[C:13](=[CH:14][CH:6]=2)[NH:12][C:11](=[O:15])[CH2:10]3)=[O:32])[CH2:27][CH2:28]1)[C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1

참가 물질

3

반응물 2

HCID 6494458(4-Benzyl-piperidin-1-yl)-acetic acidHCID 18002787HCID 18002787, 화합물

생성물 1

HCID 18002785HCID 18002785, 화합물

실험 절차

Condensation of 6-(2-aminoethanoyl)-1,3-dihydroindol-2-one hydrochloride with (4-benzylpiperidin-1-yl)acetic acid, following the procedure described in Example 6, Step 6, gave 2-(4-benzyl-piperidin-1-yl)-N-[2-oxo-2-(2-oxo-2,3-dihydro-1H-indol-5-yl)ethyl]acetamide:

출처 및 근거

ORD 기록
ord-c13dfe6a3b40406796a1ecfef3970c42
출처 데이터셋
uspto-grants-2003_11
특허 번호
US06642256B2

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