Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol → HCID 18003572, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | Bromoacetic Acid | HCID 6227 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | Ethyl isopropoxyacetate | HCID 537908 | — |
| 반응물 | (s)-2-But-3-enyloxy-3-(4-{2-[2-(4-isopropyl-phenyl)-5-methyl-oxazol-4-yl]-ethoxy}-benzo[b]thiophen-7-yl)-propionic acid | HCID 69556375 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | HCID 18003572 | HCID 18003572 | — |
반응 단계
was prepared in analogy to example 39, but using in the aldol-coupling step ethyl isopropoxy-acetate instead of butyl butoxy-acetate as white crystals of mp. 148-150°. The former reagent was synthesized as described above for but-3-enyloxy-acetic acid (see example 65) from iPrOH, NaH, and bromo-acetic acid, followed by acid catalyzed esterification with EtOH.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06642389B2 |
| 출처 데이터셋 | uspto-grants-2003_11 |
| ORD ID | ord-1d3e39c5ea0a4de897ae8f9539fa04a3 |
| 출처 메모 | uspto-grants-2003_11 |