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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 479216생성일: 2026년 10월 25일

Phosphonium, (1,2-diethoxy-2-oxoethyl)triphenyl-, chloride (1:1) → 3-{3,5-dimethyl-4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-2Z-ethoxy-acrylic acid

https://huagongshe.com/reaction/479216

반응식

참여 물질

역할이름HCID투입량
반응물Phosphonium, (1,2-diethoxy-2-oxoethyl)triphenyl-, chloride (1:1)HCID 11327835—
반응물3,5-Dimethyl-4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzaldehydeHCID 18003604—
반응물3-{3,5-dimethyl-4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-2Z-ethoxy-acrylic acid ethyl esterHCID 69556024—
생성물3-{3,5-dimethyl-4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-2Z-ethoxy-acrylic acidHCID 69556636—

반응 단계

In analogy to the procedure described in example 120 f], 3-{3,5-dimethyl-4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-2Z-ethoxy-acrylic acid ethyl ester {prepared from 3,5-dimethyl-4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzaldehyde (example 117) and (ethoxy-ethoxycarbonyl-methyl)-triphenyl-phosphonium chloride (K. K. Bach, H. R. El-Seedi, H. M. Jensen, H. B. Nielsen, I. Thomson, K. B. G. Torssell, Tetrahedron 1994, 50, 7543-7556) in analogy to the procedure described in example 114 c]} was saponified to yield 3-{3,5-dimethyl-4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-2Z-ethoxy-acrylic acid as colorless crystals.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06642389B2
출처 데이터셋uspto-grants-2003_11
ORD IDord-b362b31a68d54496a120591d5e9e9028
출처 메모uspto-grants-2003_11