Oxalyl chloride → HCID 22609552, 화합물

HRID 479396노트

반응식

HRID 479396 반응식
[C:1](Cl)(=O)[C:2]([Cl:4])=[O:3].[CH3:7][O:8][C:9]1[CH:10]=[C:11](/[CH:19]=[CH:20]/[CH:21]=C/C(O)=O)[CH:12]=[C:13]([O:17][CH3:18])[C:14]=1[O:15][CH3:16]>CN(C)C=O.C(Cl)Cl>[CH3:18][O:17][C:13]1[CH:12]=[C:11](/[CH:19]=[CH:20]/[CH:21]=[CH:1]/[C:2]([Cl:4])=[O:3])[CH:10]=[C:9]([O:8][CH3:7])[C:14]=1[O:15][CH3:16]

참가 물질

4

반응물 2

HCID 65578Oxalyl chlorideHCID 15257506HCID 15257506, 화합물

생성물 1

HCID 22609552HCID 22609552, 화합물

시약·촉매·용매 1

HCID 22350042dichloromethane N,N-dimethylformamide용매

실험 절차

After oxalyl chloride (0.055 ml; 0.63 mmol) was added to a solution of (E,E)-5-(3,4,5-trimethoxyphenyl)-2,4-pentadienoic acid (116 mg; 0.44 mmol) in dimethylformamide-methylene chloride (0.1 ml-5 ml) under ice cooling. The ice bath was removed, and the mixture was stirred at room temperature for 30 minutes. The reaction mixture was concentrated under reduced pressure to obtain crude crystals of (E,E)-5-(3,4,5-trimethoxyphenyl)-2,4-pentadienoyl chloride.

후처리

  1. customThe ice bath was removed
  2. concentrationThe reaction mixture was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-067ffdec0e5c4b5dbea8b69c9d48d5c4
출처 데이터셋
uspto-grants-2003_11
특허 번호
US06645957B2

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