p-Toluenesulfonic acid → N-[1-(1H-1,2,3-benzotriazol-1-yl)-2,2-dichloropropyl]-4-methylbenzamide

반응식

[C:1]1([CH3:10])[CH:6]=[CH:5][C:4]([C:7]([NH2:9])=[O:8])=[CH:3][CH:2]=1.[Cl:11][C:12]([Cl:16])([CH3:15])[CH:13]=O.[NH:17]1[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=2[N:19]=[N:18]1.C1(C)C=CC(S(O)(=O)=O)=CC=1>>[N:17]1([CH:13]([NH:9][C:7](=[O:8])[C:4]2[CH:5]=[CH:6][C:1]([CH3:10])=[CH:2][CH:3]=2)[C:12]([Cl:16])([Cl:11])[CH3:15])[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=2[N:19]=[N:18]1

참가 물질

반응물 4

HCID 6101p-Toluenesulfonic acid

HCID 692744-Methylbenzamide

HCID 109754962,2-Dichloropropanal

HCID 178418385HCID 178418385, 화합물

생성물 1

HCID 18770769N-[1-(1H-1,2,3-benzotriazol-1-yl)-2,2-dichloropropyl]-4-methylbenzamide

실험 절차

A suspension of p-toluamide, 2,2-dichloropropionaldehyde, benzotriazole, and p-toluenesulfonic acid was processed as described in Example 53A to provide the desired product.

출처 및 근거

ORD 기록: ord-271c1d1e3c544b26a3059121b44eee03
출처 데이터셋: uspto-grants-2003_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06645968B2

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