Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Hydroxybenzaldehyde → 4-(2-Tetrahydro-2H-pyranoxy)benzaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Hydroxybenzaldehyde | HCID 126 | — |
| 반응물 | 3,4-dihydro-2H-pyran | HCID 8080 | — |
| 반응물 | Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) | HCID 466102 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 4-(2-Tetrahydro-2H-pyranoxy)benzaldehyde | HCID 11252736 | — |
반응 단계
40.0 g of 4-hydroxybenzaldehyde are dissolved in 400 ml of abs. THF under a protective-gas atmosphere, 55.1 g of dihydropyran and 13.7 g of pyridinium p-toluenesulfonate are added, and the mixture is stirred overnight at room temperature. The solvent is removed in a rotary evaporator, and the residue is subjected to conventional work-up, giving 4-(tetrahydropyran-2-yloxy)benzaldehyde (“BA”) as a colourless oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06645991B1 |
| 출처 데이터셋 | uspto-grants-2003_11 |
| ORD ID | ord-4c452461370e4d9e8bf9bcf189ef2201 |
| 출처 메모 | uspto-grants-2003_11 |