Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(R)-2-[2-(tert-butoxy)-2-oxoethyl]-5-phenylpentanoic acid → (2R)-2-[2-(tert-butoxy)-2-oxoethyl]-5-cyclohexylpentanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (R)-2-[2-(tert-butoxy)-2-oxoethyl]-5-phenylpentanoic acid | HCID 10803584 | — |
| 촉매 | Rhodium | HCID 23948 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | (2R)-2-[2-(tert-butoxy)-2-oxoethyl]-5-cyclohexylpentanoic acid | HCID 9835906 | 89.4% |
반응 단계
A solution of (R)-2-[2-(tert-butoxy)-2-oxoethyl]-5-phenylpentanoic acid (2.2 g, 7.5 mmol) and 5%Rh/C (0.22 g) in methanol (220 ml) was stirred at room temperature, under hydrogen (150 p.s.i.) for 24 hours and then filtered through celite. The filtrate was concentrated in vacuo to leave the title compound as an oil (2.0 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06645993B2 |
| 출처 데이터셋 | uspto-grants-2003_11 |
| ORD ID | ord-cc5272357d0a4327898538824ebdcb1d |
| 출처 메모 | uspto-grants-2003_11 |