Isopropylamine → HCID 18768049, 화합물
반응식
[NH:1]([C:8]1[C:13]([Br:14])=[CH:12][N:11]=[C:10]([NH:15][C:16]2[CH:21]=[CH:20][C:19]([NH:22][C:23](=[O:27])[CH2:24][CH2:25]Cl)=[CH:18][CH:17]=2)[N:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:28]([NH2:31])([CH3:30])[CH3:29]>>[NH:1]([C:8]1[C:13]([Br:14])=[CH:12][N:11]=[C:10]([NH:15][C:16]2[CH:21]=[CH:20][C:19]([NH:22][C:23](=[O:27])[CH2:24][CH2:25][NH:31][CH:28]([CH3:30])[CH3:29])=[CH:18][CH:17]=2)[N:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1참가 물질
3
실험 절차
Using an analogous method to that described in Example 101, but starting from 4-anilino-5-bromo-2-[4-(3-chloropropionamido)anilino]pyrimidine (Method 37) and isopropylamine, the product was obtained. MS (MH+): 469, 471; HPLC (RT): 3.70.
후처리
- customthe product was obtained
- customHPLC (RT)
출처 및 근거
- ORD 기록
- ord-2dd2568e11944d8aa08141c0d27f1b26
- 출처 데이터셋
- uspto-grants-2003_11