Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 480410생성일: 2026년 10월 24일
Sodium Hydroxide → 2-Amino-4-(3,5-diacetylphenyl)imino-1,4-dihydro-1,6-dimethylpyrimidine
https://huagongshe.com/reaction/480410
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 2-Amino-4-(3,5-diacetylphenyl)amino-1,6-dimethylpyrimidinium iodide | HCID 9845352 | — |
| 반응물 | Methanol--water (1/1) | HCID 22242641 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2-Amino-4-(3,5-diacetylphenyl)imino-1,4-dihydro-1,6-dimethylpyrimidine | HCID 73089 | 99.9% |
반응 단계
A suspension of 21 g (49.3 mmole) of 2-amino-4-(3,5-diacetylphenyl)amino-1,6-dimethylpyrimidinium iodide (compound No. 2, synthesized as described in section 6.1) in 1:1 methanol/water (750 mL) at 60° C. was treated with excess 2N NaOH with cooling to maintain about 60° C. An additional 200 mL of water was added and the mixture was cooled in ice and filtered to give 14.69 g 2-amino-4-(3,5-diacetylphenyl) imino-1,4-dihydro-1,6-dimethylpyrimidine as yellow crystals, mp 219-220°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US06649797B2 |
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| 출처 데이터셋 | uspto-grants-2003_11 |
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| ORD ID | ord-46f358ec0fb94b93b1b1f6073b8d498a |
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| 출처 메모 | uspto-grants-2003_11 |
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