2-(6-Bromo-2-naphthyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole → HCID 178450052, 화합물
반응식
Br[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([C:12]1[O:13][CH2:14][C:15]([CH3:18])([CH3:17])[N:16]=1)[CH:6]=[CH:5]2.[CH3:19][CH:20]([CH3:47])[CH:21]([C:23]1[N:24]=[CH:25][N:26](C(C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[CH:27]=1)[OH:22]>>[CH3:17][C:15]1([CH3:18])[CH2:14][O:13][C:12]([C:7]2[CH:8]=[C:9]3[C:4](=[CH:5][CH:6]=2)[CH:3]=[C:2]([C:21]([C:23]2[N:24]=[CH:25][NH:26][CH:27]=2)([OH:22])[CH:20]([CH3:47])[CH3:19])[CH:11]=[CH:10]3)=[N:16]1참가 물질
3
실험 절차
2-(6-Bromo-2-naphthyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole (1.0 g) and 2-methyl-1-(1-trityl-1H-imidazol-4-yl)-1-propanol (835 mg) were used as the starting materials. By the same procedure described in Reference example 1, the titled compound (1.25 g) was obtained as a colorless amorphous powder.
출처 및 근거
- ORD 기록
- ord-a8bdbd92665e4d6192d9f4cff59ce89a
- 출처 데이터셋
- uspto-grants-2003_11