Methanol → Methyl L-ornithine monohydrochloride

HRID 480747

반응식

HRID 480747 반응식
[ClH:1].[NH2:2][C@H:3]([C:8]([OH:10])=[O:9])[CH2:4][CH2:5][CH2:6][NH2:7].[CH3:11]O>>[ClH:1].[CH3:11][O:9][C:8](=[O:10])[C@H:3]([CH2:4][CH2:5][CH2:6][NH2:7])[NH2:2]

참가 물질

3

반응물 2

HCID 887MethanolHCID 76654Ornithine hydrochloride

생성물 1

HCID 6453904Methyl L-ornithine monohydrochloride수율 97%

실험 절차

Into a stirred suspension of L-(+)-ornithine hydrochloride (Aldrich) in methanol was bubbled anhydrous hydrochloric acid gas until the solution was saturated. The reaction mixture was capped with a rubber septum and stirring was continued overnight at room temperature. The solvent was then stripped under reduced pressure and the residue triturated with ether. The resulting solid was dried under reduced pressure to afford L-(+)-ornithine methyl ester hydrochloride as a white solid (97% yield).

후처리

  1. customwas bubbled anhydrous hydrochloric acid gas until the solution
  2. customThe reaction mixture was capped with a rubber septum
  3. customthe residue triturated with ether
  4. customThe resulting solid was dried under reduced pressure

출처 및 근거

ORD 기록
ord-969ab8a01746414fa7adc2f26c944ffb
출처 데이터셋
uspto-grants-2003_11
특허 번호
US06653303B1

연결된 노트

불러오는 중…