Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acid → 5-[N'-(3,5-difluorophenylacetyl)-L-alaninyl]amino-7-(methoxyacetyl)-5,7-dihydro-6H-dibenz[b,d]azepin-6-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acid | HCID 12135350 | — |
| 반응물 | 5-amino-7-(methoxyacetyl)-5,7-dihydro-6H-dibenz[b,d]azepin-6-one hydrochloride | HCID 22312635 | — |
| 생성물 | 5-[N'-(3,5-difluorophenylacetyl)-L-alaninyl]amino-7-(methoxyacetyl)-5,7-dihydro-6H-dibenz[b,d]azepin-6-one | HCID 10229817 | — |
반응 단계
Following General Procedure D and using N-(3,5-difluorophenylacetyl)-L-alanine (Example B) and 5-amino-7-(methoxyacetyl)-5,7-dihydro-6H-dibenz[b,d]azepin-6-one hydrochloride (Example 7-G), the title compound was prepared as a colorless solid. The product was purified by flash chromatography.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06653303B1 |
| 출처 데이터셋 | uspto-grants-2003_11 |
| ORD ID | ord-0284dbf2e7ee4ffb8bace0597e1b4a6c |
| 출처 메모 | uspto-grants-2003_11 |