Uridine → 5'-O-(4-Methylbenzoyl)uridine

HRID 48089

반응식

HRID 48089 반응식
[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][CH:3]=1.[C@@H:11]1([N:20]2[CH:27]=[CH:26][C:24](=[O:25])[NH:23][C:21]2=[O:22])[O:19][C@H:16]([CH2:17][OH:18])[C@@H:14]([OH:15])[C@H:12]1[OH:13]>N1C=CC=CC=1>[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([O:18][CH2:17][C@H:16]2[O:19][C@@H:11]([N:20]3[CH:27]=[CH:26][C:24](=[O:25])[NH:23][C:21]3=[O:22])[C@H:12]([OH:13])[C@@H:14]2[OH:15])=[O:7])=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 6029UridineHCID 134054-Methylbenzoyl Chloride

생성물 1

HCID 115885775'-O-(4-Methylbenzoyl)uridine

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

4-Methylbenzoyl chloride (10 mmol) is added to a solution of uridine (10 mmol) in 20 mL of pyridine. After no further progress occurs as observed by TLC, the volatile components are evaporated in vacuo. The residue is purified using flash chromatography to give the product as a colorless oil.

후처리

  1. customthe volatile components are evaporated in vacuo
  2. customThe residue is purified

출처 및 근거

ORD 기록
ord-5fea9a53770246ee989f9ac9adc592d9
출처 데이터셋
uspto-grants-2004_03
특허 번호
US06702705B1

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