Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chloroacetyl chloride → 2-Chloro-1-[4-(2-cyanophenyl)piperazin-1-yl]ethanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chloroacetyl chloride | HCID 6577 | — |
| 반응물 | Calcium Carbonate | HCID 10112 | — |
| 반응물 | N-(2-Cyanophenyl)piperazine | HCID 2735875 | — |
| 반응물 | 2-Chloro-1-(4-o-tolylpiperazin-1-yl)ethanone | HCID 4741212 | — |
| 용매 | Methyl Ethyl Ketone | HCID 6569 | — |
| 생성물 | 2-Chloro-1-[4-(2-cyanophenyl)piperazin-1-yl]ethanone | HCID 10400554 | — |
반응 단계
Compound 17A is prepared according to the same procedure as that for 12A, using the following reactants: chloroacetyl chloride (670 μl, 8.4 mmol), 1-(2-cyanophenyl)piperazine (1.32 g, 7 mmol), calcium carbonate (2.1 g, 21 mmol), methyl ethyl ketone (30 ml).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05789412 |
| 출처 데이터셋 | uspto-grants-1998_08 |
| ORD ID | ord-ba90fcc583e242a0a902eaec2bc6b1ed |
| 출처 메모 | uspto-grants-1998_08 |