참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 3-Butenenitrile | HCID 8009 | — |
| 반응물 | 4,4'-Methylenebisbenzenediazonium bis(tetrafluoroborate) | HCID 11732010 | — |
| 촉매 | palladium(II) acetate | HCID 167845 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4-{4-[4-(3-Cyano-propenyl)-benzyl]-phenyl}-but-3-enenitrile | HCID 57091596 | 61% |
반응 단계
A suspension of 4,4′-methanediyl-bis-benzenediazonium tetrafluoroborate (11.9 g, 0.03 mol), prepared according to the method of example 6.1, allyl cyanide (8.05 g; 0.12 mol), and palladium acetate (0.135 g, 0.6 mmol) in 80 ml of ethanol is heated at 40° C. during 22 h. The heterogeneous reaction mixture is poured into 300 ml of water, extracted with ethyl acetate, washed with water, brine, dried over MgSO4, and evaporated. The crude beige product is recrystallized from 130 ml of ethanol, yielding 5.44 g (61%) of 4-{4-[4-(3-cyano-propenyl)-benzyl]-phenyl}-but-3-enenitrile as light beige crystals, melting point 128-130° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06703182B1 |
|---|
| 출처 데이터셋 | uspto-grants-2004_03 |
|---|
| ORD ID | ord-7395024a17624351a2345a5625fb037c |
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| 출처 메모 | uspto-grants-2004_03 |
|---|
