(2S,3S)-3-(5-(1-Cyanocyclopropyl)-2-methoxybenzyl)amino-2-phenylpiperidine dihydrochloride → (2S,3S)-3-(5-(1-(N-Acetyl-N-methylamino)cyclopropyl)-2-methoxybenzyl)amino-2-phenylpiperidine Dihydrochloride

HRID 481493

반응식

HRID 481493 반응식
[C:1]([N:4]([C:6]1([C:9]2[CH:10]=[CH:11][C:12]([O:29][CH3:30])=[C:13]([CH:28]=2)[CH2:14][NH:15][C@H:16]2[CH2:21][CH2:20][CH2:19][NH:18][C@H:17]2[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH2:8][CH2:7]1)[CH3:5])(=[O:3])[CH3:2].[ClH:31].Cl.C(C1(C2C=CC(OC)=C(C=2)CN[C@H]2CCCN[C@H]2C2C=CC=CC=2)CC1)#N>>[ClH:31].[ClH:31].[C:1]([N:4]([C:6]1([C:9]2[CH:10]=[CH:11][C:12]([O:29][CH3:30])=[C:13]([CH:28]=2)[CH2:14][NH:15][C@H:16]2[CH2:21][CH2:20][CH2:19][NH:18][C@H:17]2[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH2:7][CH2:8]1)[CH3:5])(=[O:3])[CH3:2]

참가 물질

3

반응물 2

HCID 9954592(2S,3S)-3-(5-(1-Cyanocyclopropyl)-2-methoxybenzyl)amino-2-phenylpiperidine dihydrochlorideHCID 57159006(2S,3S)-3-(5-(1-(N-Acetyl-N-methylamino)cyclopropyl)-2-methoxybenzyl)amino-2-phenylpiperidine

생성물 1

HCID 70136622(2S,3S)-3-(5-(1-(N-Acetyl-N-methylamino)cyclopropyl)-2-methoxybenzyl)amino-2-phenylpiperidine Dihydrochloride

실험 절차

This compound was prepared from Compound 11 in the same manner of Compound 5.

출처 및 근거

ORD 기록
ord-7cea0a2f1af74ee1b0242c5d329ab85f
출처 데이터셋
uspto-grants-1998_08
특허 번호
US05789423

연결된 노트

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