Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Adipic Acid → 5-{2-[3-Hydroxy-3-phenyl-2-pyridin-2-yl-1-(pyridin-2-ylamino)propyl]phenylcarbamoyl}pentanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Adipic Acid | HCID 196 | — |
| 반응물 | Dicyclohexylcarbodiimide | HCID 10868 | — |
| 반응물 | 1-Hydroxybenzotriazole | HCID 75771 | — |
| 반응물 | 3-(2-Aminophenyl)-1-phenyl-2-pyridin-2-yl-3-(pyridin-2-ylamino)propan-1-ol | HCID 15411858 | — |
| 생성물 | 5-{2-[3-Hydroxy-3-phenyl-2-pyridin-2-yl-1-(pyridin-2-ylamino)propyl]phenylcarbamoyl}pentanoic acid | HCID 22742197 | — |
반응 단계
Prepared from 1.5 g of 3-(2-aminophenyl)-1-phenyl-2-pyridin-2-yl-3-(pyridin-2-ylamino)propan-1-ol, 3.4 g of hexanedioic acid, 1.04 g of dicyclohexylcarbodiimide and 640 mg of benzotriazol-1-ol, analogously to example II f) Product _of molecular weight 524.6 (C31H32N4O4); MS (ESI+): 525 (M+H+): (ESI−): 523 (M−H+)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06703386B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-d843cd0da3e94fd9922673e5b7059e1a |
| 출처 메모 | uspto-grants-2004_03 |