Potassium Iodide → HCID 19063054, 화합물

HRID 482509노트

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HRID 482509 반응식
[C:1]12([C:11]3[CH:12]=[C:13]([C:18]#[C:19][C:20]4[CH:29]=[CH:28][C:23]([C:24]([O:26][CH3:27])=[O:25])=[CH:22][CH:21]=4)[CH:14]=[CH:15][C:16]=3[OH:17])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.Br[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][OH:37].C(=O)([O-])[O-].[K+].[K+].[I-].[K+]>CC(=O)CC>[C:1]12([C:11]3[CH:12]=[C:13]([C:18]#[C:19][C:20]4[CH:29]=[CH:28][C:23]([C:24]([O:26][CH3:27])=[O:25])=[CH:22][CH:21]=4)[CH:14]=[CH:15][C:16]=3[O:17][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][OH:37])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2

참가 물질

6

반응물 4

HCID 4875Potassium IodideHCID 11430Potassium CarbonateHCID 779706-Bromo-1-hexanolHCID 19063002Methyl 4-[3-(1-adamantyl)-4-hydroxyphenylethynyl]benzoate

생성물 1

HCID 19063054HCID 19063054, 화합물

시약·촉매·용매 1

HCID 6569Methyl Ethyl Ketone용매

실험 절차

2 g (5.1 mmol) of methyl 4-[3-(1-adamantyl)-4-hydroxyphenylethynyl]benzoate, 1.1 ml (8.3 mmol) of 6-bromo-1-hexanol, 1.2 g (8.8 mmol) of potassium carbonate, 20 mg of potassium iodide and 100 ml of 2-butanone were introduced into a round-bottomed flask. The reaction mixture was heated at reflux for twelve hours and was evaporated to dryness, the residue was taken up in water and ethyl acetate and the organic phase was separated by settling, dried over magnesium sulfate and evaporated.

후처리

  1. temperatureThe reaction mixture was heated
  2. temperatureat reflux for twelve hours
  3. customwas evaporated to dryness
  4. customethyl acetate and the organic phase was separated
  5. dry with materialdried over magnesium sulfate
  6. customevaporated

출처 및 근거

ORD 기록
ord-8e979760d5ce490b8ea450be9f2e774b
출처 데이터셋
uspto-grants-1998_08
특허 번호
US05798354

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