Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl Isothiocyanate → HCID 178526850, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl Isothiocyanate | HCID 2346 | — |
| 반응물 | Ethyl chloroformate | HCID 10928 | — |
| 반응물 | 2-Bromo-5-nitrothiazole | HCID 18211 | — |
| 반응물 | 3-Amino-1-benzylthiourea | HCID 737135 | — |
| 반응물 | HCID 178518950 | HCID 178518950 | — |
| 생성물 | HCID 178526850 | HCID 178526850 | 17.8% |
반응 단계
The title compound was prepared in a manner similar to that described in Example 5 starting with benzyl isothiocyanate. The intermediate 4-benzyl-3-thiosemicarbazide (1.81 g) was treated with ethyl chloroformate (1.09 g) as in Example 5. The reaction product 4-benzyl-3-hydroxy-5-mercapto-1,2,4-triazole (1.04 g) was reacted with 1.05 g of 2-bromo-5-nitrothiazole as in Example 5. Crystallization from ethanol and water gave 0.3 g of 4-benzyl-3-hydroxy-5-[(5-nitrothiazol-2-yl)mercapto]1,2,4-triazole, a yellow solid, MP 221°-224° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05798374 |
| 출처 데이터셋 | uspto-grants-1998_08 |
| ORD ID | ord-cef50e31aac14d0f9285ca29dbd13b4c |
| 출처 메모 | uspto-grants-1998_08 |