2-Methylbenzenesulfonic acid → HCID 13644521, 화합물
반응식
O[CH:2]1[C:11]2[C:6](=[CH:7][C:8]([F:12])=[CH:9][CH:10]=2)[C:5]2([C:16](=[O:17])[NH:15][C:14](=[O:18])[NH:13]2)[CH2:4][CH2:3]1.C1(C)C(S(O)(=O)=O)=CC=CC=1>C1(C)C=CC=CC=1>[F:12][C:8]1[CH:7]=[C:6]2[C:11]([CH:2]=[CH:3][CH2:4][C:5]32[C:16](=[O:17])[NH:15][C:14](=[O:18])[NH:13]3)=[CH:10][CH:9]=1참가 물질
4
실험 절차
3',4',-Dihydro-4'-hydroxy-7'-fluorospiro[imidazolidine-4,1'(2'H)-naphthalene]2,5-dione (3.2 g., 0.013 mole) was added to 75 ml. of toluene containing a trace of -toluenesulfonic acid and the mixture heated to reflux for 5 hours. The toluene was removed in vacuo and the residue triturated with diethyl ether and filtered, 2.6 g. (87% yield).
후처리
- temperatureto reflux for 5 hours
- customThe toluene was removed in vacuo
- customthe residue triturated with diethyl ether
- filtrationfiltered
출처 및 근거
- ORD 기록
- ord-1f8ff5667a1c4f4c83ce958f46f003e5
- 출처 데이터셋
- uspto-grants-1986_03
- 특허 번호
- US04575507
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