Dichloromethane → 2-Chloro-2-(methylsulfanyl)pent-4-enenitrile

HRID 482823노트

반응식

HRID 482823 반응식
[CH3:1][S:2][CH:3]([CH2:6][CH:7]=[CH2:8])[C:4]#[N:5].C(Cl)[Cl:10]>>[Cl:10][C:3]([S:2][CH3:1])([CH2:6][CH:7]=[CH2:8])[C:4]#[N:5]

참가 물질

3

반응물 2

HCID 6344Dichloromethane2회HCID 138132372-Methylthio-4-pentenenitrile

생성물 1

HCID 138132392-Chloro-2-(methylsulfanyl)pent-4-enenitrile

실험 절차

2×10-2 moles of 2-methylthio-4-pentenenitrile are then dissolved in 50 ml of dry CH2Cl2. 2×10-2 moles of SO2Cl2 dissolved in 10 ml of CH2Cl2 are added dropwise. The mixture is stirred until gas evolution has ceased (silicone oil trap). The solvent is evaporated off and distillation is carried out at 82° C. at a pressure of 12 mm of mercury. 2-Chloro-2-methylthio-4-pentene-nitrile is obtained in a yield of over 95%.

후처리

  1. additionare added dropwise
  2. customThe solvent is evaporated off
  3. distillationdistillation
  4. customis carried out at 82° C. at a pressure of 12 mm of mercury

출처 및 근거

ORD 기록
ord-1d29117cfcb046b5943ab8d33f8dd82c
출처 데이터셋
uspto-grants-1986_03
특허 번호
US04576759

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