m-Chloroperbenzoic acid → 2-(2,3-dihydro-2-methylbenzofuran-7-yl)-N-methoxy-N-methyldiazenecarboxamide

HRID 482961노트

반응식

HRID 482961 반응식
C1C=C(Cl)C=C(C(OO)=O)C=1.[CH3:12][CH:13]1[CH2:17][C:16]2[CH:18]=[CH:19][CH:20]=[C:21]([NH:22][NH:23][C:24]([N:26]([O:28][CH3:29])[CH3:27])=[O:25])[C:15]=2[O:14]1>C(Cl)Cl>[CH3:12][CH:13]1[CH2:17][C:16]2[CH:18]=[CH:19][CH:20]=[C:21]([N:22]=[N:23][C:24]([N:26]([O:28][CH3:29])[CH3:27])=[O:25])[C:15]=2[O:14]1

참가 물질

4

반응물 2

HCID 70297m-Chloroperbenzoic acidHCID 135358281-(2,3-Dihydro-2-methylbenzofuran-7-yl)-4-methoxy-4-methylsemicarbazide

생성물 1

HCID 135897272-(2,3-dihydro-2-methylbenzofuran-7-yl)-N-methoxy-N-methyldiazenecarboxamide

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

반응 조건

온도
0 °C

실험 절차

A solution of 4.4 g of MCPBA in 150 ml of methylene chloride was added drop-by-drop (over 15 minutes) to a stirred mixture of 5.4 g of 1E and 150 ml of methylene chloride, at 0° C. The mixture then was stirred at 0° C. for 15 minutes, washed with 10% aqueous sodium carbonate solution, then cold water, dried (MgSO4) and the solvent was evaporated, to give 1, as an orange oil.

후처리

  1. washwashed with 10% aqueous sodium carbonate solution
  2. dry with materialcold water, dried (MgSO4)
  3. customthe solvent was evaporated
  4. customto give 1

출처 및 근거

ORD 기록
ord-432cacf7615e412eacac71397cd4188b
출처 데이터셋
uspto-grants-1986_03
특허 번호
US04577011

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