Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Chloro-2-fluorobenzoic acid → (8-Chloro-1-methyl-1,2,3,4-tetrahydrobenzo[e][1,4]diazepin-5-ylidenemethyl)phosphonic acid diethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Chloro-2-fluorobenzoic acid | HCID 99152 | — |
| 반응물 | (1-Methyl-1,2,3,4-tetrahydrobenzo[e][1,4]diazepin-5-ylidenemethyl)phosphonic acid diethyl ester | HCID 72957243 | — |
| 생성물 | (8-Chloro-1-methyl-1,2,3,4-tetrahydrobenzo[e][1,4]diazepin-5-ylidenemethyl)phosphonic acid diethyl ester | HCID 86585812 | — |
반응 단계
(8-chloro-1-methyl-1,2,3,4-tetrahydrobenzo[e][1,4]diazepin-5-ylidenemethyl)phosphonic acid diethyl ester was prepared in an analogous fashion to (1-methyl-1,2,3,4-tetrahydrobenzo[e][1,4]diazepin-5-ylidenemethyl)phosphonic acid diethyl ester, as described in Example 1 by replacing 2-fluorobenzoic acid with 4-chloro-2-fluorobenzoic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06703387B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-cafcf1e2c6564f24b4144d972fce84b7 |
| 출처 메모 | uspto-grants-2004_03 |