Methanol, 1-methoxy-, 1-acetate → 1,3-Dipivaloyl-2-methoxymethyl glycerol

HRID 483674노트

반응식

HRID 483674 반응식
[C:1]([O:7][CH2:8][CH:9]([CH2:11][O:12][C:13](=[O:18])[C:14]([CH3:17])([CH3:16])[CH3:15])[OH:10])(=[O:6])[C:2]([CH3:5])([CH3:4])[CH3:3].O.C1(C)C=CC(S(O)(=O)=O)=CC=1.[C:31]([O:34][CH2:35]OC)(=O)C>CCCCCC>[C:1]([O:7][CH2:8][CH:9]([CH2:11][O:12][C:13](=[O:18])[C:14]([CH3:17])([CH3:16])[CH3:15])[O:10][CH2:31][O:34][CH3:35])(=[O:6])[C:2]([CH3:5])([CH3:4])[CH3:3]

참가 물질

5

반응물 3

HCID 78087Methanol, 1-methoxy-, 1-acetateHCID 521998p-Toluenesulfonic acid monohydrateHCID 136911551,3-Dipivaloyl glycerol

생성물 1

HCID 109796251,3-Dipivaloyl-2-methoxymethyl glycerol

시약·촉매·용매 1

HCID 8058Hexane용매

실험 절차

50.45 g of 1,3-dipivaloyl glycerol was dissolved in 200 ml of methoxymethyl acetate. After the addition of 2.5 g of p-toluenesulfonic acid monohydrate, the mixture was stirred for 1 hr then diluted with 200 ml of hexane and washed twice with 200 ml saturated aqueous sodium carbonate, once with aqueous NaCl solutions, dried over anhydrous magnesium sulfate and concentrated in vacuo to afford 1,3-dipivaloyl-2-methoxymethyl glycerol as a colorless oil.

후처리

  1. washwashed twice with 200 ml saturated aqueous sodium carbonate, once with aqueous NaCl solutions
  2. dry with materialdried over anhydrous magnesium sulfate
  3. concentrationconcentrated in vacuo

출처 및 근거

ORD 기록
ord-ce832fdd316046a394efeca9e7a52d66
출처 데이터셋
uspto-grants-1993_07
특허 번호
US05225590

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