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HRID 483758생성일: 2026년 10월 25일

2-Chloro-4-nitropyridine 1-oxide → Pyridine, 2-chloro-4-methoxy-, 1-oxide

https://huagongshe.com/reaction/483758

반응식

참여 물질

역할이름HCID투입량
반응물2-Chloro-4-nitropyridine 1-oxideHCID 84433—
반응물SodiumHCID 5360545—
반응물Sodium MethoxideHCID 10942334—
용매MethanolHCID 887—
생성물Pyridine, 2-chloro-4-methoxy-, 1-oxideHCID 15593755—

반응 단계

Sodium (0.46 g) is dissolved in absolute methanol (50 ml) and the resultant solution of sodium methoxide is added to a solution of 2-chloro-4-nitropyridine-1-oxide (3.5 g, prepared as described in Example 1) in methanol (10 ml). The reaction mixture is allowed to stand at room temperature for 50 hours and is then subjected to rotary evaporation to give 2-chloro-4-methoxypyridine-1-oxide.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호USRE034313
출처 데이터셋uspto-grants-1993_07
ORD IDord-20eeab3c45f14020a6979e4c216e0572
출처 메모uspto-grants-1993_07